Description: C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK. It can act in a variety of cancer cell lines. Target: Apoptosis. Smiles: CCCCCCCCCC CCC\C=C\[C@@H](O)[C@H](CO)NC(=O)CCCCC. References: Zhu Q, et, al. C6-ceramide...

C6 ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides. C6 ceramide mediates many diverse biological activities including apoptosis, activation of protein...