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Item number: Cay27636-1

Derazantinib is a multi-kinase inhibitor. It is a pan inhibitor of FGF receptors (FGFRs, IC50s = 4.5, 1.8, 4.5, and 34 nM for FGFR1, -2, -3, and -4, respectively) and also inhibits 10 receptor tyrosine kinases, 8 non-receptor tyrosine kinases, and the calcium/calmodulin-dependent protein kinase QIK in a panel of 297...

Keywords:	ARQ 087, (6R)-6-(2-fluorophenyl)-5,6-dihydro-N-[3-[2-[(2-methoxyethyl)amino]ethyl]phenyl]-benzo[h]quinazolin-2-amine
Application:	Multi-kinase inhibitor
CAS	1234356-69-4
MW:	468.6 D

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Derazantinib

Item number: TGM-TQ0228-100mg

Description: Derazantinib (ARQ-087) is a potent, ATP-competitive, orally active tyrosine kinase inhibitor with IC50 values of 4.5/1.8/4.35/3.4 nM for chondrocyte FGFR1/FGFR2/FGFR3/FGFR4, respectively. Target: FGFR. Smiles: COCCNCCc1cccc(Nc2ncc3C[C@@H](c4ccccc4F)c4ccccc4-c3n2)c1. References: Balek L, et al. ARQ 087...

Keywords:	ARQ-087
Application:	Multi-kinase inhibitor
CAS	1234356-69-4
MW:	468.57 D

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