3 products were found matching "1223403-58-4"!
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LOXO-101
Item number: Cay27056-1
LOXO-101 is an inhibitor of the tropomyosin-related kinases TrkA, TrkB, and TrkC (IC50s = 2-20 nM). It is selective for TrkA, -B, and -C over a panel of 226 kinases at 1 µM. LOXO-101 inhibits the growth of CUTO-3.29, KM12, and MO-91 patient-derived cancer cell lines (IC50s = In vivo, LOXO-101 (60 and 200 mg/kg)...
| Keywords: | ARRY-470, Larotrectinib,... |
| Application: | TrkA / TrkB / TrkC inhibitor |
| CAS | 1223403-58-4 |
| MW: | 428.4 D |
From 67.00€
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LOXO-101
Item number: LKT-L589940.100
Inhibitor of tropomyosin kinase receptors TRKA, TRKB, and TRKC
| Keywords: | LOXO 101, LOXO101, ARRY 470, ARRY-470, ARRY470, Larotrectinib |
| Application: | TrkA / TrkB / TrkC inhibitor |
| CAS | 1223403-58-4 |
| MW: | 428.44 D |
From 123.00€
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Larotrectinib
Item number: TGM-T5995-100mg
Description: Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase, demonstrating high selectivity exclusively for the TRK family of receptors (IC50s = 2-20 nM). Target: Apoptosis, Trk receptor. Smiles: O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F. References: Doebele R C ,...
| Keywords: | LOXO-101, ARRY-470 |
| Application: | Antineoplastic, Tropomyosin receptor kinase inhibitor |
| CAS | 1223403-58-4 |
| MW: | 428.44 D |
From 32.00€
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