Larotrectinib

Item number	Size	Delivery time	Price
TGM-T5995-1mg	1 mg	7 - 10 business days*	32.00€
TGM-T5995-5mg	5 mg	7 - 10 business days*	68.00€
TGM-T5995-1mL	1 ml	7 - 10 business days*	74.00€
TGM-T5995-10mg	10 mg	7 - 10 business days*	91.00€
TGM-T5995-25mg	25 mg	7 - 10 business days*	158.00€
TGM-T5995-50mg	50 mg	7 - 10 business days*	248.00€
TGM-T5995-100mg	100 mg	7 - 10 business days*	374.00€
TGM-T5995-500mg	500 mg	7 - 10 business days*	863.00€

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Description: Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase,... more

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Product information "Larotrectinib"

Description: Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase, demonstrating high selectivity exclusively for the TRK family of receptors (IC50s = 2-20 nM). Target: Apoptosis, Trk receptor. Smiles: O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F. References: Doebele R C , Davis L E , Vaishnavi A , et al. An oncogenic NTRK fusion in a soft tissue sarcoma patient with response to the tropomyosin-related kinase (TRK) inhibitor LOXO-101[J]. Cancer Discovery, 2015, 5(10):1049-1057.

Keywords:	LOXO-101, ARRY-470
Supplier:	TargetMol
Supplier-Nr:	T5995

Properties

MW:	428.44 D
Formula:	C21H22F2N6O2

Database Information

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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