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Item number: Cay28777-1

AC-264613 is an agonist of proteinase-activated receptor 2 (PAR2). It induces calcium mobilization, phosphatidylinositol hydrolysis, and cell proliferation in NIH3T3 cells expressing PAR2 (EC50s = 100, 125.8, and 31.6 nM, respectively). AC-264613 (3 µg/paw) induces paw edema and thermal hyperalgesia in rats.Formal...

Keywords:	(3R,4S)-rel-2-oxo-4-phenyl-3-pyrrolidinecarboxylic acid, 2-[1-(3-bromophenyl)ethylidene]hydrazide
Application:	PAR2 agonist
CAS	1051487-82-1
MW:	400.3 D

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AC-264613

Item number: TGM-T4186-10mg

Description: AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613(AC264613) activated PAR2 signaling in cellular proliferation assays,...

Keywords:	AC264613
Application:	PAR2 agonist
CAS	1051487-82-1
MW:	400.28 D

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