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Item number: Cay19966-1

CC-885 is a modulator of the E3 ligase protein cereblon with antiproliferative effects on human myeloid leukemia cell lines. It forms a complex with cereblon and the cell cycle regulator and translation termination factor GSPT1. The antitumour activity of CC-885 relies on cereblon-dependent ubiquitination and...

Keywords:	N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-urea
Application:	CRBN modulator
CAS	1010100-07-8
MW:	440.9 D

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CC-885

Item number: TGM-T14893-100mg

Description: CC-885 is a modulator of cereblon (CRBN). It has potent anti-tumour activity. Target: Ligand for E3 Ligase, Others. Smiles: O=C1N(CC=2C1=CC=C(CNC(NC3=CC(Cl)=C(C)C=C3)=O)C2)C4C(=O)NC(=O)CC4. References: Mary E. Matyskiela, et al. A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin...

Application:	CRBN modulator
CAS	1010100-07-8
MW:	440.88 D

From 52.00€ *

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