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SRT 2183
Item number: Cay43526-10
SRT 2183 is an activator of sirtuin 1 (SIRT1, EC50 = 0.36 µM). However, it was found only to bind fluorophore-labeled SIRT1 and also inhibits 14 targets, including cannabinoid receptor 1 (CB1), adenosine receptor 3 (A3), and phosphodiesterase 5 (PDE5), in a panel of 100 receptors, enzymes, ion channels, and...
| Keywords: | N-[2-[3-[[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]imidazo[2,1-b]thiazol-6-yl]phenyl]-2-naphthalenecarboxamide |
| Application: | SIRT1 activator |
| CAS | 1001908-89-9 |
| MW: | 468.58 D |
From 186.00€
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SRT 2183
Item number: TGM-T16932-100mg
Description: SRT 2183 is a selective activator of Sirtuin-1 (SIRT1, EC1.5 : 0.36 µM). Target: Apoptosis, Sirtuin. Smiles: O[C@@H]1CCN(Cc2csc3nc(cn23)-c2ccccc2NC(=O)c2ccc3ccccc3c2)C1. References: Scuto A, et al. SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of...
| CAS | 1001908-89-9 |
| MW: | 468.57 D |
From 44.00€
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