Products from RevMAb Biosciences
RevMAb Biosciences, Inc. is a biotechnology company focused on the development of recombinant monoclonal antibodies using a revolutionary technology that does not require cell fusion and hybridoma generation. The mission of the company from San Francisco, California is to promote personal health by accelerating biomedical research and advancing disease diagnosis. RevMAb seeks to accomplish this by providing superior monoclonal antibodies to customers in research and diagnostic fields.
More information at: www.adipogen.com/revmab-biosciences
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5-Formylcytosines (5-fC) DNA Matched Antibody Pair
Item number: REV-31-1369-MK-KI01
5-Formylcytosine (5fC) is a pyrimidine nitrogen base derived from cytosine and a recently discovered modification of DNA. Just as 5-hydroxymethylcytosine (5-hmC) is generated when the Tet family of cytosine oxygenase enzymes converts 5-methylcytosine (5-mC), it has been shown that continued activity of the Tet...
| Keywords: | 5-fC |
| Application: | ELISA |
| Species reactivity: | broad |
926.00€
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Anti-Trimethyl-Histone H3 (Lys36), Rabbit Monoclonal (RM491)
Item number: REV-31-1383-00-C100
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Histone H3 has...
| Keywords: | Anti-H3 K36me3 |
| Application: | ELISA, CHIP, Multiplex |
| Host: | Rabbit |
| Species reactivity: | human, vertebrates |
660.00€
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Anti-alpha-synuclein (SYUA), Rabbit Monoclonal (RM492)
Item number: REV-31-1384-00-R100
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that...
| Keywords: | Anti-SYUA |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
541.00€
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Anti-EGFR (human), Rabbit Monoclonal (RM493)
Item number: REV-31-1385-00-R100
EGFR (Epidermal growth factor receptor, HER1, ErbB1) belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4. EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor...
| Keywords: | Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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Anti-ER-alpha (human), Rabbit Monoclonal (RM494)
Item number: REV-31-1386-00-R100
Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE)...
| Keywords: | Anti-ER, Anti-ESR, Anti-ESR1, Anti-ER-alpha, Anti-Estrogen receptor, Anti-Estradiol receptor, Anti-Nuclear receptor... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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Anti-CDX2 (human), Rabbit Monoclonal (RM495)
Item number: REV-31-1387-00-R100
CDX2 is a caudal-type homeobox gene that encodes an intestine-specific transcription factor expressed early in intestinal development and that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. CDX2 plays a role in early embryonic development of the intestinal...
| Keywords: | Anti-CDX3, Anti-CDX2, Anti-CDX-3, Anti-Homeobox protein CDX-2, Anti-Caudal-type homeobox protein 2 |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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Anti-CD68 (human), Rabbit Monoclonal (RM496)
Item number: REV-31-1388-00-R100
CD68 [Macrosialin, GP110, SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 could play a role in phagocytic activities of tissue macrophages, both...
| Keywords: | Anti-CD68, Anti-Gp110, Anti-Macrosialin |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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Anti-CD45 (human), Rabbit Monoclonal (RM497)
Item number: REV-31-1389-00-R100
CD45 (LCA, Leukocyte Common Antigen, Protein tyrosine phosphatase, receptor type, C, PTPRC) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45...
| Keywords: | Anti-L-CA, Anti-CD45, Anti-T200, EC=3.1.3.48, Anti-Leukocyte common antigen, Anti-Receptor-type tyrosine-protein... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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Anti-LAIR1 (human), Rabbit Monoclonal (RM498)
Item number: REV-31-1390-00-R100
LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on the cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in the recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of...
| Keywords: | Anti-CD305, Anti-LAIR1, Anti-hLAIR1, Anti-LAIR-1, Anti-Leukocyte-associated immunoglobulin-like receptor 1 |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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Anti-Galectin-9 (human), Rabbit Monoclonal (RM499)
Item number: REV-31-1391-00-R100
Galectin-9 (Gal-9), a beta-galactoside-binding protein, primarily plays an immunosuppressive role in the tumor microenvironment, via binding with several cell surface receptors expressed on immune cells. Although Gal-9 was initially identified as a ligand for T-cell immunoglobulin and mucin domain-containing...
| Keywords: | Anti-Gal-9, Anti-LGALS9, Anti-Ecalectin, Anti-Galectin-9, Anti-Tumor antigen HOM-HD-21 |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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Anti-Phospho-DNA-PKcs (Ser2056) (human), Rabbit...
Item number: REV-31-1392-00-R100
DNA-dependent protein kinase (DNA-PK) is an important factor in the repair of double-stranded breaks in DNA. Cells lacking DNA-PK or in which DNA-PK is inhibited fail to show proper nonhomologous end-joining (NHEJ). DNA-PK is composed of two DNA-binding subunits (Ku70 and Ku86) and one 450 kDa catalytic subunit...
| Keywords: | Anti-phospho-p460, Anti-phospho-HYRC, Anti-phospho-DNPK1, Anti-phospho-PRKDC, Anti-phospho-DNA-PKcs, Anti-phospho-DNA-PK... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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Anti-CD27 (human), Rabbit Monoclonal (RM501)
Item number: REV-31-1393-00-R100
CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes...
| Keywords: | Anti-T14, Anti-CD27, Anti-TNFRSF7, Anti-CD27 antigen, Anti-CD27L receptor, Anti-T-cell activation antigen CD27, Anti-Tumor... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
541.00€
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