WISP1, His, Mouse

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z06404-100	100 µg		-		Request delivery time estimate		497.00€
GSC-Z06404-500	500 µg		-		Request delivery time estimate		1,680.00€

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The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles... more

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Product information "WISP1, His, Mouse"

The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and secreted by GSCs. Silencing WISP1 markedly disrupts GSC maintenance, reduces tumor-supportive TAMs (M2), and potently inhibits GBM growth. WISP1 signals through Integrin alpha6beta1-Akt to maintain GSCs by an autocrine mechanism and M2 TAMs through a paracrine manner.

Keywords:	Ccn4, ELM-1, CCN family member 4, WNT1-inducible-signaling pathway protein 1
Supplier:	GenScript
Supplier-Nr:	Z06404

Properties

Conjugate:	No
Species reactivity:	mouse
MW:	39.4 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K22471 \| Matching products
UniProt ID :	O54775 \| Matching products
Gene ID :	GeneID 22402 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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