49 products were found matching "K22471"!

The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and secreted by GSCs. Silencing WISP1 markedly disrupts GSC maintenance, reduces tumor-supportive TAMs...

Protein function: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan. Suppresses tumor growth in vivo. [The UniProt Consortium]

Protein function: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. WNT1-Inducible Signaling Pathway Protein 1, also known as CCN4, is a matricellular protein that in humans is encoded by the WISP1 gene. It is induced by WNT1 and belongs to the CCN family, which includes connective tissue growth factor, cysteine-rich-61, and...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: WNT1 inducible signaling pathway protein 1 Protein function: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in...

ELISA Type: Sandwich. Sensitivity: 46.875pg/mL. Range: 78.125--5000pg/mL. Protein function: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L)...

Protein function: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to...

Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human WISP1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human WISP1. Next,...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse...

Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 23-367aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged. Target Protein Sequence: TALSPTPTTM TFTPAPLEET ITRPEFCKWP CECPQAPPRC PLGVSLITDG CECCKICAQQ LGDNCTEAAV CDPHRGLYCD YSGDRPRYAI...