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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-APrEST79543.100 | 100 µl | - | - |
7 - 10 business days* |
247.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs)... more
Product information "TRIM71 PrEST Antigen"
Protein function: E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance (Probable). Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. In addition, participates in post-transcriptional mRNA repression in a miRNA independent mechanism (PubMed:23125361). Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1. Specific regulator of miRNA biogenesis. Binds to miRNA MIR29A hairpin and postranscriptionally modulates MIR29A levels, which indirectly regulates TET proteins expression (PubMed:28431233). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
| Keywords: | LIN41, EC=2.3.2.27, Protein lin-41 homolog, E3 ubiquitin-protein ligase TRIM71, Tripartite motif-containing protein 71, RING-type E3 ubiquitin transferase TRIM71 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | APrEST79543 |
Properties
| Application: | Control antigen |
| Conjugate: | No |
| Host: | E.coli |
| Species reactivity: | human |
Database Information
| KEGG ID : | K12035 | Matching products |
| UniProt ID : | Q2Q1W2 | Matching products |
| Gene ID | GeneID 131405 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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