TRIM71 PrEST Antigen

TRIM71 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST79543.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs)... more
Product information "TRIM71 PrEST Antigen"
Protein function: E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance (Probable). Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. In addition, participates in post-transcriptional mRNA repression in a miRNA independent mechanism (PubMed:23125361). Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1. Specific regulator of miRNA biogenesis. Binds to miRNA MIR29A hairpin and postranscriptionally modulates MIR29A levels, which indirectly regulates TET proteins expression (PubMed:28431233). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: LIN41, EC=2.3.2.27, Protein lin-41 homolog, E3 ubiquitin-protein ligase TRIM71, Tripartite motif-containing protein 71, RING-type E3 ubiquitin transferase TRIM71
Supplier: Atlas Antibodies
Supplier-Nr: APrEST79543

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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