SMO (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-3342-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-3342-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: G protein-coupled receptor that probably associates with the patched protein... more

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Product information "SMO (human), recombinant protein"

Protein function: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7, GLI2 and GLI3 in the cilia (PubMed:19592253). Interacts with DLG5 at the ciliary base to induce the accumulation of KIF7 and GLI2 at the ciliary tip for GLI2 activation. [The UniProt Consortium]

Keywords:	Protein smoothened, Protein Gx, Recombinant Human SMO Protein
Supplier:	Absea
Supplier-Nr:	PP-3342-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	18 kD
Format:	Lyophilized

Database Information

KEGG ID :	K06226 \| Matching products
UniProt ID :	Q99835 \| Matching products
Gene ID :	GeneID 6608 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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