SIRT6, Recombinant, Human (Sirtuin 6, Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin-6, SIR2-like Pr

Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human ageing. Source: Recombinant human Sirtuin 6, full length, with N-terminal GST tag, expressed in E. coli. Molecular Weight: 65kD , Applications: , Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.