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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-TMPY-03125-200ug | 200 µg | - |
7 - 10 business days* |
903.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family,... more
Product information "SHP-2 Protein, Mouse, Recombinant (His)"
Description: SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric acid monoesters. They dephosphorylate EGFR, JAK2 and TYK2 kinases, promoting oncogenic transformation. SHP2 is widely expressed, with highest levels in heart, brain, and skeletal muscle. SHP2 acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. It also dephosphorylates ROCK2 at Tyr-722 resulting in stimulation of its RhoA binding activity.
| Keywords: | SHP-2, SH-PTP3, PTP2C, SH-PTP2, PTP1D, Syp, SAP-2, 2700084A17Rik, Shp2, AW536184, protein tyrosine phosphatase, non-receptor type 11 |
| Supplier: | TargetMol |
| Supplier-Nr: | TMPY-03125 |
Properties
| Conjugate: | No |
| MW: | 69.5 kD |
Database Information
| KEGG ID : | K07293 | Matching products |
| UniProt ID : | P35235 | Matching products |
| Gene ID : | GeneID 19247 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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