SET8 (human recombinant)

SET8 (human recombinant)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10319-100 100 µg -

1 - 10 business days

413.00€
 
Methylation of lysine can promote transcriptional activation or repression and is critical in... more
Product information "SET8 (human recombinant)"
Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated. SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and transcriptional activation. SET8 is also a novel regulator of p53, mono-methylating lysine 382 of the tumor suppressor. SET8's ability to suppress p53 transcriptional activity implies that it may play a significant role in tumorigenesis.
Keywords: N-lysine methyltransferase SETD8, Histone-lysine N-methyltransferase SETD8, EC=2.1.1.43
Supplier: Cayman Chemical
Supplier-Nr: 10319-100

Properties

Application: Enzyme activity
Conjugate: No
Expressed in: E.coli
MW: 21.1 kD
Purity: >95% estimated by SDS-PAGE

Database Information

KEGG ID : K11428 | Search using KEGG ID
UniProt ID : Q9NQR1 | Search using UniProt ID

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H319
P Phrases: P264, P280, P305+P351+P338, P332+P313, P337+P313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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