Semaphorin-5A/SEMA5A Protein (recombinant human)

Semaphorin-5A/SEMA5A Protein (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB0820.10 10 µg - - -

10 - 15 business days*

202.00€
 
Endotoxin level: < 1.0 EU/µg of the protein by LAL method. Protein function: Bifunctional axonal... more
Product information "Semaphorin-5A/SEMA5A Protein (recombinant human)"
Endotoxin level: < 1.0 EU/µg of the protein by LAL method. Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. [The UniProt Consortium]
Keywords: SEMAF, SEMA5A, Sema F, Semaphorin-F, Semaphorin-5A
Supplier: Assay Genie
Supplier-Nr: RPCB0820

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
Purity: >95% (SDS-PAGE)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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