SEMA5A (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-11580-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-11580-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans,... more

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Product information "SEMA5A (human), recombinant protein"

Protein function: Bifunctional axonal guidance cue regulated by sulfated proteoglycans, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. [The UniProt Consortium]

Keywords:	Semaphorin-5A, Semaphorin-F, Sema F, Recombinant Human SEMA5A Protein
Supplier:	Absea
Supplier-Nr:	PP-11580-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	33 kD
Format:	Lyophilized

Database Information

KEGG ID :	K06841 \| Matching products
UniProt ID :	Q13591 \| Matching products
Gene ID :	GeneID 9037 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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