RAPGEF3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6456-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-6456-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that... more

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Product information "RAPGEF3 (human), recombinant protein"

Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP- induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin. [The UniProt Consortium]

Keywords:	Rap guanine nucleotide exchange factor 3, Exchange factor directly activated by cAMP 1, Exchange protein directly activated by cAMP 1, EPAC 1, Rap1 guanine-nucleotide-exchange factor directly activated by cAMP, cAMP-regulated guanine nucleotide exchange f
Supplier:	Absea
Supplier-Nr:	PP-6456-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	18.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K08014 \| Matching products
UniProt ID :	O95398 \| Matching products
Gene ID :	GeneID 10411 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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