PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)

PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-TMPH-02277-20ug 20 µg -

7 - 10 business days*

281.00€
TGM-TMPH-02277-100ug 100 µg -

7 - 10 business days*

536.00€
TGM-TMPH-02277-1mg 1 mg

7 - 10 business days*

2,302.00€
 
Description: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to... more
Product information "PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)"
Description: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity. Dephosphorylates CDC73. Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification.
Keywords: SH-PTP2, PTPN11, Protein-tyrosine phosphatase 2C, SH-PTP3, Protein-tyrosine phosphatase 1D, Tyrosine-protein phosphatase non-receptor type 11
Supplier: TargetMol
Supplier-Nr: TMPH-02277

Properties

Conjugate: No
MW: 73.9 kD

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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