Prostaglandin F Synthase (human recombinant)

Prostaglandin F Synthase (human recombinant)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007940-100 100 µg -

6 - 10 business days*

Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence... more
Product information "Prostaglandin F Synthase (human recombinant)"
Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence similarity to aldo-keto reductase family members. It exhibits two related primary activities, catalyzing the isomerization of PGH2 to PGF2alpha (PGH2 9,11-endoperoxide reductase activity), as well as the formation of 11beta-PGF2alpha from PGD2 (PGD2 11-ketoreductase activity) in the presence of NADPH. The enzyme also exhibits reductase activities toward carbonyl compounds such at nitroacetophenone, nitrobenzaldehyde, and 9,10-phenanthrene quinine (PQ). Cayman's human recombinant PGFS has been expressed and purified from an E.coli overexpression system. Enzyme activity was determined by monitoring the change in absorbance at 340 nm using PGD2 as the substrate and NADPH as the cofactor (PGD2 11-ketoreductase activity). Synonyms: AKR1C3, Aldo-keto Reductase Family 1 Member C3, 3-alpha-HSD Type II (Brain), 17-beta-HSD 5, PGFS. Purity: >85% estimated by SDS-PAGE. Source: active recombinant C-terminal His-tagged protein expressed in E. coli. Amino Acids: 1-323. MW: 40.4 kDa. Formulation: A solution in 100 mM sodium phosphate, pH 7.2, containing 20% glycerol, 100 mM sodium chloride, and 1 mM EDTA. UniProt Accession #: P42330.
Keywords: DD3, DD3, DDH1, DD-3, DD-3, AKR1C3, HA1753, HA1753, 17-beta-HSD 5, 17-beta-HSD 5, 3-alpha-HSD type 2, 3-alpha-HSD type 2, 3-alpha-HSD type II, brain, 3-alpha-HSD type II, brain, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydro
Supplier: Cayman Chemical
Supplier-Nr: 10007940


Application: Enzyme activity, WB
Conjugate: No
MW: 37 kD
Purity: >85% estimated by SDS-PAGE
Format: Solution

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H316, H319
P Phrases: P264, P280, P305+351+338, P332+313, P337+313
Our products are for laboratory research use only: Not for administration to humans!
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