35 products were found matching "K04119"!
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CRT0036521
Item number: Cay36600-50
CRT0036521 is an inhibitor of prostaglandin F synthase, also known as aldo-keto reductase 1C3 (AKR1C3, IC50 = 0.013 µM). It is selective for prostaglandin F synthase/AKR1C3 over AKR1C1, AKR1C2, and AKR1C4 (IC50s = 20, >30, and >30 µM, respectively).Formal Name: 3-[(3,4-dihydro-2(1H)-isoquinolinyl)sulfonyl]-benzoic...
| Keywords: | 3-[(3,4-dihydro-2(1H)-isoquinolinyl)sulfonyl]-benzoic acid |
| Application: | Prostaglandin F synthase/AKR1C3 inhibitor |
| CAS | 327092-81-9 |
| MW: | 317.4 D |
From 44.00€
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Anti-AKR1C3, C-terminal
Item number: ARG63695.100
Protein function: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active...
| Keywords: | Anti-DD3, Anti-DD-3, Anti-DDH1, Anti-PGFS, Anti-HA1753, Anti-AKR1C3, EC=1.-.-.-, EC=1.3.1.20, EC=1.1.1.64, EC=1.1.1.112,... |
| Application: | ELISA, WB |
| Host: | Goat |
| Species reactivity: | human |
871.00€
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Prostaglandin F Synthase (human, recombinant)
Item number: Cay10007940-100
Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence similarity to aldo-keto reductase family members. It exhibits two related primary activities, catalyzing the isomerization of PGH2 to PGF2alpha (PGH2 9,11-endoperoxide reductase activity), as well as the formation of...
| Keywords: | DD3, DD3, DDH1, DD-3, DD-3, AKR1C3, HA1753, HA1753, 17-beta-HSD 5, 17-beta-HSD 5, 3-alpha-HSD type 2, 3-alpha-HSD type 2,... |
| Application: | Enzyme activity, WB |
| MW: | 37 kD |
687.00€
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Anti-AKR1C3
Item number: NSJ-R33228-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Aldo-keto reductase family 1, member C3 Protein function: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and...
| Keywords: | Anti-DD3, Anti-DD-3, Anti-DDH1, Anti-PGFS, Anti-HA1753, Anti-AKR1C3, EC=1.-.-.-, EC=1.1.1.64, EC=1.3.1.20, EC=1.1.1.239,... |
| Application: | WB, ELISA (peptide) |
| Host: | Goat |
| Species reactivity: | human |
836.00€
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ASP9521
Item number: Cay27308-10
ASP9521 is an inhibitor of 17beta-hydroxysteroid dehydrogenase type 5/aldo-keto reductase 1C3 (17beta-HSD5/AKR1C3, IC50 = 120 nM). It is selective for 17beta-HSD5/AKR1C3 over AKR1C2 (IC50 = 20 µM). ASP9521 inhibits conversion of androstenedione into testosterone by 17beta-HSD5/AKR1C3 (IC50s = 11 and 49 nM for human...
| Keywords: | [4-(2-hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)-methanone |
| Application: | 17beta-HSD5/AKR1C3 inhibitor |
| CAS | 1126084-37-4 |
| MW: | 330.4 D |
From 93.00€
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Aldo-keto reductase family 1 member C3 (AKR1C3), human,...
Item number: CSB-EP001544HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-323aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD...
| Keywords: | DD3, DDH1, DD-3, PGFS, HA1753, AKR1C3, 17-beta-HSD 5, 3-alpha-HSD type 2, Prostaglandin F synthase, 3-alpha-HSD type II,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 63.9 kD |
From 219.00€
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Aldo-keto reductase family 1 member C3 (AKR1C3), human,...
Item number: CSB-EP001544HUc7.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-323aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP...
| Keywords: | DD3, DDH1, DD-3, PGFS, HA1753, AKR1C3, 17-beta-HSD 5, 3-alpha-HSD type 2, Prostaglandin F synthase, 3-alpha-HSD type II,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 43.8 kD |
From 219.00€
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AKR1C3-IN-1
Item number: TGM-T7406-100mg
Description: AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM). Target: Dehydrogenase, NADPH. Smiles: OC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccccc2C1. References: Jamieson S M F , Brooke D G , Heinrich D , et al. 3-(3,4-Dihydroisoquinolin-2(1 H )-ylsulfonyl)benzoic Acids: Highly Potent and Selective...
| Application: | Prostaglandin F synthase/AKR1C3 inhibitor |
| CAS | 327092-81-9 |
| MW: | 317.36 D |
From 30.00€
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AKR1C3 Protein, Human, Recombinant (His)
Item number: TGM-TMPJ-00962-10ug
Description: AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols....
| Keywords: | 3-alpha-HSD Type II Brain, 17-beta-HSD 5, 17-Beta-HSD 5, 3-Alpha-HSD Type 2, 17-beta-Hydroxysteroid Dehydrogenase Type 5,... |
| MW: | 38 kD |
From 172.00€
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NEW
Human AKR1C3 (Aldo-keto Reductase Family 1 Member C3)...
Item number: G-AEKE03199.96
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AKR1C3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AKR1C3....
| Keywords: | HA1753, AKR1C3, Prostaglandin F synthase, 3-alpha-HSD type II, brain, Dihydrodiol dehydrogenase 3, Dihydrodiol... |
| Application: | ELISA |
| Species reactivity: | human |
694.00€
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NEW
Anti-AKR1C3 [R08-8G6] Monoclonal Antibody
Item number: G-AGMB01427.20
AKR1C3 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids. Acts as a NAD(P)(H)-dependent 3-, 17- and 20-ketosteroid reductase on the steroid...
| Keywords: | Anti-HA1753, Anti-AKR1C3, Anti-Prostaglandin F synthase, Anti-3-alpha-HSD type II, brain, Anti-Dihydrodiol dehydrogenase... |
| Application: | WB, ICC/IF, FC, IP |
| Host: | Rabbit |
| Species reactivity: | human |
134.00€
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Aldo-Keto Reductase Family 1 Member C3, aa1-323, Human,...
Item number: A1334-70P.100
AKR1C3, also known as PGFS, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the...
| Keywords: | DDH1, DD-3, EC=1.-.-.-, EC=1.3.1.20, EC=1.1.1.64, EC=1.1.1.63, EC=1.1.1.112, EC=1.1.1.188, EC=1.1.1.213, 17-beta-HSD 5,... |
From 636.00€
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