39 products were found matching "K04119"!
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Anti-AKR1C3 / Aldo-keto reductase family 1 member C3,...
Item number: NSJ-FY13421
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. AKR1C3 antibody targets Aldo-keto reductase family 1 member C3 (AKR1C3), a cytosolic oxidoreductase enzyme that plays a key role in steroid hormone metabolism, prostaglandin signaling, and cellular...
| Keywords: | Anti-HA1753, Anti-AKR1C3, Anti-Prostaglandin F synthase, Anti-3-alpha-HSD type II, brain, Anti-Dihydrodiol dehydrogenase... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
790.00€
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CRT0036521
Item number: Cay36600-50
CRT0036521 is an inhibitor of prostaglandin F synthase, also known as aldo-keto reductase 1C3 (AKR1C3, IC50 = 0.013 µM). It is selective for prostaglandin F synthase/AKR1C3 over AKR1C1, AKR1C2, and AKR1C4 (IC50s = 20, >30, and >30 µM, respectively).Formal Name: 3-[(3,4-dihydro-2(1H)-isoquinolinyl)sulfonyl]-benzoic...
| Keywords: | 3-[(3,4-dihydro-2(1H)-isoquinolinyl)sulfonyl]-benzoic acid |
| Application: | Prostaglandin F synthase/AKR1C3 inhibitor |
| CAS | 327092-81-9 |
| MW: | 317.4 D |
From 45.00€
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Anti-AKR1C3, C-terminal
Item number: ARG63695.100
Protein function: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active...
| Keywords: | Anti-DD3, Anti-DD-3, Anti-DDH1, Anti-PGFS, Anti-HA1753, Anti-AKR1C3, EC=1.-.-.-, EC=1.3.1.20, EC=1.1.1.64, EC=1.1.1.112,... |
| Application: | ELISA, WB |
| Host: | Goat |
| Species reactivity: | human |
871.00€
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Prostaglandin F Synthase (human, recombinant)
Item number: Cay10007940-100
Human prostaglandin F synthase (PGFS) is a ~37 kDa monomeric protein with high sequence similarity to aldo-keto reductase family members. It exhibits two related primary activities, catalyzing the isomerization of PGH2 to PGF2alpha (PGH2 9,11-endoperoxide reductase activity), as well as the formation of...
| Keywords: | DD3, DD3, DDH1, DD-3, DD-3, AKR1C3, HA1753, HA1753, 17-beta-HSD 5, 17-beta-HSD 5, 3-alpha-HSD type 2, 3-alpha-HSD type 2,... |
| Application: | Enzyme activity, WB |
| MW: | 37 kD |
709.00€
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Anti-AKR1C3
Item number: NSJ-R33228-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Aldo-keto reductase family 1, member C3 Protein function: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and...
| Keywords: | Anti-DD3, Anti-DD-3, Anti-DDH1, Anti-PGFS, Anti-HA1753, Anti-AKR1C3, EC=1.-.-.-, EC=1.1.1.64, EC=1.3.1.20, EC=1.1.1.239,... |
| Application: | WB, ELISA (peptide) |
| Host: | Goat |
| Species reactivity: | human |
836.00€
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ASP9521
Item number: Cay27308-10
ASP9521 is an inhibitor of 17beta-hydroxysteroid dehydrogenase type 5/aldo-keto reductase 1C3 (17beta-HSD5/AKR1C3, IC50 = 120 nM). It is selective for 17beta-HSD5/AKR1C3 over AKR1C2 (IC50 = 20 µM). ASP9521 inhibits conversion of androstenedione into testosterone by 17beta-HSD5/AKR1C3 (IC50s = 11 and 49 nM for human...
| Keywords: | [4-(2-hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)-methanone |
| Application: | 17beta-HSD5/AKR1C3 inhibitor |
| CAS | 1126084-37-4 |
| MW: | 330.4 D |
From 97.00€
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Aldo-keto reductase family 1 member C3 (AKR1C3), human,...
Item number: CSB-EP001544HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-323aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD...
| Keywords: | DD3, DDH1, DD-3, PGFS, HA1753, AKR1C3, 17-beta-HSD 5, 3-alpha-HSD type 2, Prostaglandin F synthase, 3-alpha-HSD type II,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 63.9 kD |
From 219.00€
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Aldo-keto reductase family 1 member C3 (AKR1C3), human,...
Item number: CSB-EP001544HUc7.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-323aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP...
| Keywords: | DD3, DDH1, DD-3, PGFS, HA1753, AKR1C3, 17-beta-HSD 5, 3-alpha-HSD type 2, Prostaglandin F synthase, 3-alpha-HSD type II,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 43.8 kD |
From 219.00€
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Anti-AKR1C3 Recombinant Monoclonal, clone 4D12
Item number: CSB-RA825204A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: AKR1C3. Antigen Species: Human
| Keywords: | Anti-DD3, Anti-DD-3, Anti-DDH1, Anti-PGFS, Anti-AKR1C3, Anti-HA1753, Anti-17-beta-HSD 5, Anti-3-alpha-HSD type 2,... |
| Application: | ELISA, IF, FC |
| Host: | Rabbit |
| Species reactivity: | human |
From 201.00€
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AKR1C3-IN-1
Item number: TGM-T7406-100mg
Description: AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM). Target: Dehydrogenase, NADPH. Smiles: OC(=O)c1cccc(c1)S(=O)(=O)N1CCc2ccccc2C1. References: Jamieson S M F , Brooke D G , Heinrich D , et al. 3-(3,4-Dihydroisoquinolin-2(1 H )-ylsulfonyl)benzoic Acids: Highly Potent and Selective...
| Application: | Prostaglandin F synthase/AKR1C3 inhibitor |
| CAS | 327092-81-9 |
| MW: | 317.36 D |
From 30.00€
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AKR1C3 Protein, Human, Recombinant (His)
Item number: TGM-TMPJ-00962-10ug
Description: AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols....
| Keywords: | 3-alpha-HSD Type II Brain, 17-beta-HSD 5, 17-Beta-HSD 5, 3-Alpha-HSD Type 2, 17-beta-Hydroxysteroid Dehydrogenase Type 5,... |
| MW: | 38 kD |
From 172.00€
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ASP-9521
Item number: TGM-T4529-100mg
Description: ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human). Target: NADPH. Smiles: COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC(C)(C)O)CC1. References: Kikuchi A, et al. In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of...
| Keywords: | ASP9521 |
| Application: | 17beta-HSD5/AKR1C3 inhibitor |
| CAS | 1126084-37-4 |
| MW: | 330.42 D |
From 30.00€
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