Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P1001-37V1.10 | 10 µg | - | - |
3 - 19 business days* |
1,037.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
p70S6K is responsible for the phosphorylation of 40S ribosomal protein S6 and is ubiquitously... more
Product information "p70 S6 Kinase, active, Recombinant, Human (p70 S6K)"
p70S6K is responsible for the phosphorylation of 40S ribosomal protein S6 and is ubiquitously expressed in human adult tissues (1). p70S6K is activated by serum stimulation and this activation is inhibited by wortmannin and rapamycin. p70S6K activity undergoes changes in the cell cycle and increases 20-fold in G1 cells released from G0 (2). p70S6K activation requires sequential phosphorylations at proline-directed residues in the putative autoinhibitory pseudosubstrate domain, as well as T389, a site phosphorylated by phosphoinositide-dependent kinase 1 (PDK-1). Source: Recombinant full-length human p70 S6 Kinase (p70S6K) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_003161. , Molecular Mass: The approximate molecular weight is 76kD. Activity: The specific activity of p70S6K was determined to be 76 nmol/min/mg using a synthetic peptide substrate (CKRRRLASLR) (see activity assay protocol). , Storage and Stability: This product is stable at < -70° C for at least 6 months from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Keywords: | S6K1, STK14A, P70S6K1, RPS6KB1, p70 S6KA, p70-S6K 1, S6K-beta-1, EC=2.7.11.1, p70 S6K-alpha, p70 S6 kinase alpha, Ribosomal protein S6 kinase I, p70 ribosomal S6 kinase alpha, Ribosomal protein S6 kinase beta-1, Serine/threonine-protein kinase 14A |
Supplier: | United States Biological |
Supplier-Nr: | P1001-37V1 |
Properties
Conjugate: | No |
Species reactivity: | human |
Format: | Purified |
Database Information
KEGG ID : | K04688 | Matching products |
UniProt ID : | P23443 | Matching products |
Gene ID | GeneID 6198 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed