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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-HDFP1435.10 | 10 µg | - |
9 - 20 business days* |
1,605.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Ligand-gated chloride channel which is a component of the heteropentameric... more
Product information "Nanodisc Human GBRG2-Strep Protein"
Protein function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:2538761, PubMed:29950725). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:23909897, PubMed:25489750, PubMed:27864268). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (PubMed:23909897, PubMed:25489750). The alpha2/beta2/gamma2 receptor exhibits synatogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity. Functions also as histamine receptor and mediates cellular responses to histamine. [The UniProt Consortium]
| Keywords: | GABRG2, GABA(A) receptor subunit gamma-2, Gamma-aminobutyric acid receptor subunit gamma-2 |
| Supplier: | Assay Genie |
| Supplier-Nr: | HDFP1435 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | human |
Database Information
| KEGG ID : | K05186 | Matching products |
| UniProt ID : | P18507 | Matching products |
| Gene ID : | GeneID 2566 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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