Nampt, Recombinant, Mouse, (His) (Visfatin/PBEF, PBEF1, Pre-B Cell Colony Enhancing Factor 1, Nicoti

Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. Biological Activity: Shows adipogenic effects in stimulated differentiating 3T3-L1 cells. Sequence: Mouse Nampt (visfatin/PBEF) (aa 1-491) is fused at the C-terminus to a His-tag. Storage and Stability: Short-term Storage: +4°C, Long-term Storage: -20°C, Working aliquots are stable for up to 3 months when stored at -20°C.