KDM7A (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-10248-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-10248-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Histone demethylase required for brain development. Specifically demethylates... more

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Product information "KDM7A (human), recombinant protein"

Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate. [The UniProt Consortium]

Keywords:	Lysine-specific demethylase 7A, JmjC domain-containing histone demethylation protein 1D, Lysine-specific demethylase 7, [histone H3]-dimethyl-L-lysine9 demethylase 7A, Recombinant Human KDM7A Protein
Supplier:	Absea
Supplier-Nr:	PP-10248-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	22 kD
Format:	Lyophilized

Database Information

KEGG ID :	K11445 \| Matching products
UniProt ID :	Q6ZMT4 \| Matching products
Gene ID :	GeneID 80853 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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