KDM5D (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-10076.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-10076.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: Histone demethylase that specifically demethylates 'Lys-4' of histone H3,... more

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Product information "KDM5D (human), recombinant protein"

Protein function: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes, in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks. [The UniProt Consortium]

Keywords:	Lysine-specific demethylase 5D, Histocompatibility Y antigen, H-Y, Histone demethylase JARID1D, Jumonji/ARID domain-containing protein 1D, Protein SmcY, [histone H3]-trimethyl-L-lysine(4) demethylase 5D, Recombinant Human KDM5D Protein
Supplier:	Absea
Supplier-Nr:	PP-10076

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	18 kD
Format:	Solution

Database Information

KEGG ID :	K11446 \| Matching products
UniProt ID :	Q9BY66 \| Matching products
Gene ID :	GeneID 8284 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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