113 products were found matching "K11446"!
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Anti-JARID1C
Item number: A301-034A
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'....
| Keywords: | Anti-KDM5C, Anti-DXS1272E, EC=1.14.11.-, Anti-Protein SmcX, Anti-Protein Xe169, Anti-Histone demethylase JARID1C,... |
| Application: | WB, IP, ChIP-Seq |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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Anti-JARID1A/RBP2
Item number: A300-897A
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'....
| Keywords: | Anti-KDM5A, Anti-RBBP-2, Anti-JARID1A, EC=1.14.11.-, Anti-Histone demethylase JARID1A, Anti-Lysine-specific demethylase... |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 165.00€
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Anti-JARID1C
Item number: A301-035A
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'....
| Keywords: | Anti-KDM5C, Anti-DXS1272E, EC=1.14.11.-, Anti-Protein SmcX, Anti-Protein Xe169, Anti-Histone demethylase JARID1C,... |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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Anti-JARID1B
Item number: A301-813A
Protein function: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9....
| Keywords: | Anti-CT31, Anti-PLU-1, Anti-KDM5B, Anti-JARID1B, Anti-RBP2-H1, EC=1.14.11.-, Anti-Cancer/testis antigen 31, Anti-Histone... |
| Application: | WB, IP, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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Anti-JARID1D/SMCY
Item number: A301-751A
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'....
| Keywords: | Anti-HY, Anti-H-Y, Anti-KDM5D, EC=1.14.11.-, Anti-Protein SmcY, Anti-Histone demethylase JARID1D, Anti-Histocompatibility... |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human |
From 165.00€
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JARID1A(KDM5A, RBBP2), human recombinant protein,...
Item number: BPS-50110
Human JARID1A, also known as KDM5A and RBBP2, GenBank Accession #NM_001042603), full length [a.a. 1-1162(end)] with C-terminal FLAG-tag, MW= 125 kDa, expressed in Sf9 cells via a baculovirus expression system.
| Keywords: | RBBP-2, JARID1A, Histone demethylase JARID1A, Lysine-specific demethylase 5A, Retinoblastoma-binding protein 2,... |
| Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| MW: | 125 kD |
752.00€
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CPI-455
Item number: Cay22127-1
CPI-455 is an inhibitor of the lysine demethylase 5 family (KDM5A-D). CPI-455 binds to the demethylase active site and selectively inhibits KDM5A-D (IC50s = 2-10 nM) over KDM2-4, 6, and 7 family members (IC50s = 1 to >25 µM). It increases histone H3K4me2/3 methylation in vitro and decreases the number of...
| Keywords: | 4,7-dihydro-6-(1-methylethyl)-7-oxo-5-phenyl-pyrazolo[1,5-a]pyrimidine-3-carbonitrile |
| Application: | KDM5A/B/C histone demethylase inhibitor |
| CAS | 1628208-23-0 |
| MW: | 278.3 D |
From 40.00€
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PBIT
Item number: Cay16272-5
Jumonji AT-rich interactive domain 1 (JARID1) demethylases mediate the removal of methyl groups from trimethylated lysine 4 on histone 3 (H3K4me3). PBIT is a reversible, cell-permeable inhibitor of JARID1 family demethylases (IC50s = 6, 3, 4.9, and 28 µM for JARID1A, JARID1B, JARID1C, and JARID1D, respectively). It...
| Keywords: | 2-p-tolyl-1,2-Benzisothiazolin-3-one, 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one |
| Application: | JARID1B inhibitor |
| CAS | 2514-30-9 |
| MW: | 241.3 D |
From 56.00€
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PLU-1 human recombinant protein
Item number: BPS-50121
Human Plu-1, also known as JARID1B and KDM5B (GenBank Accession No. NM_006618) (amino-acids 2-751) with N-terminal HIS-FLAG-tag, MW=88 kDa, expressed in Sf9 cells via a baculovirus expression system.
| Keywords: | CT31, PLU-1, KDM5B, RBP2-H1, JARID1B, Cancer/testis antigen 31, Histone demethylase JARID1B, Lysine-specific demethylase... |
| Application: | Enzyme kinetics, inhibitor screening, HTS |
| MW: | 88 kD |
700.00€
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JARID1A Chemiluminescent Assay Kit
Item number: BPS-50513
The JARID1A Chemiluminescent Assay Kit is designed to measure JARID1A activity for screening and profiling applications. The kit comes in a convenient format with a 96-well strip plate precoated with methylated histone H3 peptide substrate, primary antibody, the secondary HRP-labeled antibody, demethylase assay...
| Keywords: | KDM5A, RBBP2, |
| Application: | Studying enzyme kinetics, HTS applications |
| Species reactivity: | human |
1,123.00€
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KDM5-C70
Item number: TGM-T15648-2mg
Description: KDM5-C70 is an ethyl ester derivative of KDM5-C49 and functions as an effective, cell-permeable, pan-KDM5 histone demethylase inhibitor. It exhibits an antiproliferative effect in myeloma cells and induces a genome-wide elevation of H3K4me3 levels. Target: Histone Demethylase. Smiles:...
| Application: | KDM5B (JARID1B) inhibitor |
| CAS | 1596348-32-1 |
| MW: | 336.43 D |
From 36.00€
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Anti-KDM5C / Jarid1C / SMCX, clone 2E4-E1-G8
Item number: ARG53982.100
Protein function: Histone demethylase that specifically demethylates 'Lys- 4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'....
| Keywords: | Anti-KDM5C, Anti-DXS1272E, EC=1.14.11.-, Anti-Protein SmcX, Anti-Protein Xe169, Anti-Histone demethylase JARID1C,... |
| Application: | WB, ICC, IF |
| Host: | Mouse |
| Species reactivity: | human |
658.00€
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