Interleukin-17 (IL-17)

Protein Length: Gly24-Ala155. Protein Tag: N terminal containing a HIS tag. Interleukin 17A (IL-17A) is the original member of the IL17 family of structurally related cytokines (IL-17 A to IL17F) that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17A is a pro-inflammatory cytokine produced primarily by T cells and is commonly associated with the allergic response facilitating the release of other cytokines, chemokines and prostaglandins from a variety of cell types. IL-17A exists in vitro as a homodimer of two 132 amino acid chains. RANDOX recombinant IL-17A comprises a 132 amino acid fragment (24-155) corresponding to IL-17A monomer coding sequence and is expressed in E. coli with an aminoterminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.