IGFLR1 (human):Fc (human) (rec.)

IGFLR1 (human):Fc (human) (rec.)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-40B-0087-C050 50 µg -

3 - 9 business days

Human IGFLR1 (aa 23-154) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized.... more
Product information "IGFLR1 (human):Fc (human) (rec.)"
Human IGFLR1 (aa 23-154) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNFR family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
Keywords: IGF-like Family Receptor 1, Transmembrane Protein 149, TMEM149, U2 Small Nuclear RNA Auxiliary Factor 1-like 4
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40B-0087-C050


Application: Bioassays
Conjugate: No
Expressed in: Human cells
Origin: Human
MW: 50 kD
Format: Lyophilized

Database Information

UniProt ID : Q9H665 | Search using UniProt ID

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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