Human KRAS, recombinant (G12V, N-6His)

Item number	Size	Datasheet	SDS	Delivery time	Price
NOV-CR64.10ug	10 µg	-	-	10 - 14 business days*	43.00€
NOV-CR64.50ug	50 µg	-	-	10 - 14 business days*	128.00€
NOV-CR64.500ug	500 µg	-	-	10 - 14 business days*	638.00€
NOV-CR64.1mg	1 mg	-	-	10 - 14 business days*	956.00€

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Recombinant Human GTPase Kras is produced by our E.coli expression system and the target gene... more

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Product information "Human KRAS, recombinant (G12V, N-6His)"

Recombinant Human GTPase Kras is produced by our E.coli expression system and the target gene encoding Thr2-Cys185(Gly12Val) is expressed with a 6His tag at the N-terminus. Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306). [The UniProt Consortium]

Keywords:	KRAS, KRAS2, Recombinant Human KRAS (G12V, N-6His)
Supplier:	Novoprotein
Supplier-Nr:	CR64

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	23.6 kD
Format:	Lyophilized

Database Information

KEGG ID :	K07827 \| Matching products
UniProt ID :	P01116 \| Matching products

Handling & Safety

Storage:	-20°C (+4 °C for short term storage)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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