Human HER3, recombinant (C-mFc)

Item number	Size	Datasheet	SDS	Delivery time	Price
NOV-C05M.10ug	10 µg	-	-	10 - 15 business days*	59.00€
NOV-C05M.50ug	50 µg	-	-	10 - 15 business days*	175.00€
NOV-C05M.500ug	500 µg	-	-	10 - 15 business days*	1,488.00€
NOV-C05M.1mg	1 mg	-	-	10 - 15 business days*	2,225.00€

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Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-3 is produced by our Mammalian expression... more

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Product information "Human HER3, recombinant (C-mFc)"

Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-3 is produced by our Mammalian expression system and the target gene encoding Ser20-Thr643 is expressed with a mouse IgG1 Fc tag at the C-terminus. Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908). [The UniProt Consortium]

Keywords:	HER3, ERBB3, EC=2.7.10.1, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, Recombinant Human HER3 (C-mFc)
Supplier:	Novoprotein
Supplier-Nr:	C05M

Properties

Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	95.1 kD
Format:	Lyophilized

Database Information

KEGG ID :	K05084 \| Matching products
UniProt ID :	P21860 \| Matching products

Handling & Safety

Storage:	-20°C (+4 °C for short term storage)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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