Human HER3 (C-6His-Avi), biotinylated

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NOV-CY54.20ug	20 µg	-		-	10 - 15 business days*		288.00€
NOV-CY54.100ug	100 µg	-		-	10 - 15 business days*		776.00€

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Biotinylated Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-3 is produced by our... more

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Product information "Human HER3 (C-6His-Avi), biotinylated"

Biotinylated Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-3 is produced by our Mammalian expression system and the target gene encoding Ser20-Thr643 is expressed with a 6His, Avi tag at the C-terminus. Protein function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908). [The UniProt Consortium]

Keywords:	HER3, ERBB3, EC=2.7.10.1, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, Biotinylated Human HER3 (C-6His-Avi)
Supplier:	Novoprotein
Supplier-Nr:	CY54

Properties

Conjugate:	Biotin
Host:	Human cells
Species reactivity:	human
MW:	71.3 kD
Format:	Lyophilized

Database Information

KEGG ID :	K05084 \| Matching products
UniProt ID :	P21860 \| Matching products

Handling & Safety

Storage:	-20°C (+4 °C for short term storage)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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