Her2/ErbB2, His, Mouse

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z03904-100	100 µg		-		7 - 10 business days*		484.00€
GSC-Z03904-500	500 µg		-		7 - 10 business days*		1,613.00€

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ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane... more

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Product information "Her2/ErbB2, His, Mouse"

ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane.

Keywords:	Erbb2, p185erbB2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Receptor tyrosine-protein kinase erbB-2
Supplier:	GenScript
Supplier-Nr:	Z03904

Properties

Conjugate:	No
Species reactivity:	mouse
MW:	70.74 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K05083 \| Matching products
UniProt ID :	P70424 \| Matching products
Gene ID :	GeneID 13866 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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