CACNA1C (human), recombinant protein

CACNA1C (human), recombinant protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PP-4493-L.20 20 µg - -

10 - 14 business days*

115.00€
ABS-PP-4493-L.100 100 µg - -

10 - 14 business days*

205.00€
 
Protein function: Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives... more
Product information "CACNA1C (human), recombinant protein"
Protein function: Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:8392192, PubMed:7737988, PubMed:9087614, PubMed:9013606, PubMed:9607315, PubMed:12176756, PubMed:17071743, PubMed:11741969, PubMed:8099908, PubMed:12181424, PubMed:29078335, PubMed:29742403, PubMed:16299511, PubMed:20953164, PubMed:15454078, PubMed:15863612, PubMed:17224476, PubMed:24728418, PubMed:26253506, PubMed:27218670, PubMed:23677916). Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm (PubMed:15454078, PubMed:15863612, PubMed:17224476, PubMed:24728418, PubMed:26253506). Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells (PubMed:28119464). Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group (Probable). [The UniProt Consortium]
Keywords: Voltage-dependent L-type calcium channel subunit alpha-1C, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, Voltage-gated calcium channel subunit alpha Cav1.2, Recombinant Human CACNA1C Protein
Supplier: Absea
Supplier-Nr: PP-4493-L

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 12 kD
Format: Lyophilized

Handling & Safety

Storage: -20°C (protect from light & moisture)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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