Anthrax Toxin Receptor 1 Protein (recombinant human)

Anthrax Toxin Receptor 1 Protein (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PKSH033297.10 10 µg -

7 - 16 business days*

152.00€
E-PKSH033297.50 50 µg -

7 - 16 business days*

446.00€
 
Protein Construction: Recombinant Human Anthrax Toxin Receptor 1 is produced by our Mammalian... more
Product information "Anthrax Toxin Receptor 1 Protein (recombinant human)"
Protein Construction: Recombinant Human Anthrax Toxin Receptor 1 is produced by our Mammalian expression system and the target gene encoding Glu33-Lys321 is expressed with a 6His tag at the C-terminus. Sequence: Glu33-Lys321. Fusion tag: C-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 38 kDa. Protein function: Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI). Protein function: Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. [The UniProt Consortium]
Keywords: ATR, ANTXR1, Anthrax toxin receptor 1, Tumor endothelial marker 8, Recombinant Human Anthrax Toxin Receptor 1 Protein
Supplier: Elabscience
Supplier-Nr: E-PKSH033297

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
MW: 33.6 kD
Format: Lyophilized

Handling & Safety

Storage: -80°C
Shipping: +4°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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