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Item number: ABS-PQ-3553.100
Protein function: Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia...
| Keywords: | TREM2, TREM-2, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 17 kD |
From 270.00€
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Item number: ABS-PQ-3556.100
Protein function: Forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta protein 42, a cleavage product of the amyloid-beta precursor protein APP, and mediates its uptake and degradation by microglia...
| Keywords: | TREM2, TREM-2, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2 |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 14 kD |
From 270.00€
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Item number: ABS-PQ-3559.100
Protein function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the...
| Keywords: | PSC5, PSMB1, Macropain subunit C5, Proteasome gamma chain, Proteasome component C5, Proteasome subunit beta type-1,... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 25 kD |
From 270.00€
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Item number: ABS-PQ-3560.100
Protein function: PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. [The UniProt Consortium]
| Keywords: | CYPC, PPIase C, Rotamase C, Cyclophilin C, Peptidyl-prolyl cis-trans isomerase C |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 22 kD |
From 270.00€
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Item number: ABS-PQ-3562.100
Protein function: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. [The UniProt Consortium]
| Keywords: | N2A3, CRMP2, DRP-2, ULIP-2, DPYSL2, CRMP-2, Unc-33-like phosphoprotein 2, Collapsin response mediator protein 2,... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 15 kD |
From 270.00€
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Item number: ABS-PQ-3565.100
Protein function: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the...
| Keywords: | NRCAM, Nr-CAM, hBravo, KIAA0343, Ng-CAM-related, Neuronal surface protein Bravo, Neuronal cell adhesion molecule,... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 65 kD |
From 270.00€
*
Item number: ABS-PQ-357-L.100
Protein function: Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons- containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the...
| Keywords: | Organic anion transporter 7, OAT7, Organic anion/short-chain fatty acid exchanger, Solute carrier family 22 member 9,... |
| Expressed in: | human cells |
| Origin: | human |
| MW: | 40 kD |
From 295.00€
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Item number: ABS-PQ-3570-L.100
Protein function: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration...
| Keywords: | FLN, FLNA, FLN-A, ABP-280, Filamin-1, Filamin-A, Alpha-filamin, Non-muscle filamin, Actin-binding protein 280, Endothelial... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 11 kD |
From 295.00€
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Item number: ABS-PQ-3571-L.100
Protein function: Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for...
| Keywords: | p18, UBC9, UBE2I, SUMO-protein ligase, Ubiquitin-protein ligase I, Ubiquitin carrier protein I, Ubiquitin carrier protein... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 19 kD |
From 295.00€
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Item number: ABS-PQ-3572-L.100
Protein function: Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the...
| Keywords: | Fh1, FLNB, FLN1L, FLN-B, ABP-278, Filamin-B, Filamin-3, Beta-filamin, Truncated ABP, ABP-280 homolog, Filamin homolog 1,... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 20 kD |
From 295.00€
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Item number: ABS-PQ-3573.100
Protein function: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical...
| Keywords: | GRIA1, GluA1, GLUH1, GluR-A, GluR-1, GluR-K1, Glutamate receptor 1, AMPA-selective glutamate receptor 1, Glutamate... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 71 kD |
From 270.00€
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Item number: ABS-PQ-3577.100
Protein function: [Gasdermin-D]: Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27281216). This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety...
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 51 kD |
From 270.00€
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