UBE2I (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PQ-3571-L.20	20 µg		-	-	10 - 15 business days*		295.00€
ABS-PQ-3571-L.100	100 µg		-	-	10 - 15 business days*		565.00€

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Protein function: Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and... more

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Product information "UBE2I (human), recombinant protein"

Protein function: Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity (PubMed:26620705). [The UniProt Consortium]

Keywords:	p18, UBC9, UBE2I, SUMO-protein ligase, Ubiquitin-protein ligase I, Ubiquitin carrier protein I, Ubiquitin carrier protein 9, SUMO-conjugating enzyme UBC9, Ubiquitin-conjugating enzyme E2 I, RING-type E3 SUMO transferase UBC9
Supplier:	Absea
Supplier-Nr:	PQ-3571-L

Properties

Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	19 kD
Purity:	>85%
Format:	Lyophilized

Database Information

KEGG ID :	K10577 \| Matching products
UniProt ID :	P63279 \| Matching products
Gene ID :	GeneID 7329 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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