Proteins and Enzymes

Proteins are found in every cell and form the basis of all biological processes. As molecular tools, they perform countless vital tasks in the body, for example by transporting metabolites, catalyzing chemical reactions, enabling cell movement or regulating gene expression. We offer a wide range of protein products, including enzymes, recombinant proteins and hormones. These products support researchers in molecular biology, cell biology, biochemistry and other scientific fields and can be used in a variety of applications, such as enzymatic assays, Western blots or protein-protein interaction studies.

Proteins are found in every cell and form the basis of all biological processes. As molecular tools, they perform countless vital tasks in the body, for example by transporting metabolites,... read more »
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Proteins and Enzymes

Proteins are found in every cell and form the basis of all biological processes. As molecular tools, they perform countless vital tasks in the body, for example by transporting metabolites, catalyzing chemical reactions, enabling cell movement or regulating gene expression. We offer a wide range of protein products, including enzymes, recombinant proteins and hormones. These products support researchers in molecular biology, cell biology, biochemistry and other scientific fields and can be used in a variety of applications, such as enzymatic assays, Western blots or protein-protein interaction studies.

10787 from 11002 pages
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Nanodisc Human GPR17 Protein
Nanodisc Human GPR17 Protein

Item number: G-HDFP285.10

Protein function: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. [The UniProt Consortium]
Keywords: R12, GPR17, P2Y-like receptor, UDP/CysLT receptor, G-protein coupled receptor 17, Uracil nucleotide/cysteinyl leukotriene...
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR18 Protein
Nanodisc Human GPR18 Protein

Item number: G-HDFP286.10

Protein function: Receptor for endocannabinoid N-arachidonyl glycine (NAGly) (PubMed:16844083, PubMed:24762058, PubMed:27572937). However, conflicting results about the role of NAGly as an agonist are reported (PubMed:27018161). Can also be activated by plant-derived and synthetic cannabinoid agonists...
Keywords: GPCRW, GPR18, NAGly receptor, G-protein coupled receptor 18, N-arachidonyl glycine receptor
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR22 Protein
Nanodisc Human GPR22 Protein

Item number: G-HDFP289.10

Protein function: Orphan G-protein coupled receptor. Seems to act through a G(i)/G(o) mediated pathway (PubMed:18539757). May be involved in ciliogenesis. [The UniProt Consortium]
Keywords: G-protein coupled receptor 22
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR35 Protein
Nanodisc Human GPR35 Protein

Item number: G-HDFP297.10

Protein function: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. [The UniProt Consortium]
Keywords: GPR35, KYNA receptor, Kynurenic acid receptor, G-protein coupled receptor 35
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR37 Protein
Nanodisc Human GPR37 Protein

Item number: G-HDFP298.10

Protein function: Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade. [The UniProt Consortium]
Keywords: PAELR, GPR37, ETBR-LP-1, Prosaposin receptor GPR37, G-protein coupled receptor 37, Endothelin B receptor-like protein 1,...
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR4 Protein
Nanodisc Human GPR4 Protein

Item number: G-HDFP300.10

Protein function: Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC), and GNA12/GNA13/Rho pathways (PubMed:12955148, PubMed:17462861, PubMed:22110680, PubMed:20211729). Acidosis-induced GPR4 activation increases paracellular...
Keywords: GPR4, GPR6C.l, G-protein coupled receptor 4, G-protein coupled receptor 6C.l
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR42 Protein
Nanodisc Human GPR42 Protein

Item number: G-HDFP301.10

Protein function: Probable G protein-coupled receptor that may be activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that may play a role in the regulation of whole-body energy homeostasis and/or in intestinal immunity. [The UniProt Consortium]
Keywords: GPR42, GPR42P, G-protein coupled receptor 42
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR52 Protein
Nanodisc Human GPR52 Protein

Item number: G-HDFP303.10

Protein function: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are...
Keywords: G-protein coupled receptor 52
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR6 Protein
Nanodisc Human GPR6 Protein

Item number: G-HDFP304.10

Protein function: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons. [The UniProt Consortium]
Keywords: GPR6, G-protein coupled receptor 6, Sphingosine 1-phosphate receptor GPR6
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR62 Protein
Nanodisc Human GPR62 Protein

Item number: G-HDFP306.10

Protein function: Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538). Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin...
Keywords: GPR62, hGPCR8, G-protein coupled receptor 62, G-protein coupled receptor GPCR8, G-protein coupled receptor KPG_005
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human GPR78 Protein
Nanodisc Human GPR78 Protein

Item number: G-HDFP308.10

Protein function: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. [The UniProt Consortium]
Keywords: GPR78, G-protein coupled receptor 78
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
Nanodisc Human HCAR2 Protein
Nanodisc Human HCAR2 Protein

Item number: G-HDFP319.10

Protein function: Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)- protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses...
Keywords: HCAR2, GPR109A, Niacin receptor 1, Nicotinic acid receptor, G-protein coupled receptor 109A, G-protein coupled receptor...
Expressed in: Human cells
Origin: human
1,693.00€ *
Review
10787 from 11002 pages