Nanodisc Human GPR4 Protein

Nanodisc Human GPR4 Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HDFP300.10 10 µg -

9 - 20 business days*

1,693.00€
 
Protein function: Proton-sensing G-protein coupled receptor couples to multiple intracellular... more
Product information "Nanodisc Human GPR4 Protein"
Protein function: Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC), and GNA12/GNA13/Rho pathways (PubMed:12955148, PubMed:17462861, PubMed:22110680, PubMed:20211729). Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells through the GNA12/GNA13/Rho GTPase signaling pathway (PubMed:32058960). In the brain may mediate central respiratory sensitivity to CO(2)H(+). [The UniProt Consortium]
Keywords: GPR4, GPR6C.l, G-protein coupled receptor 4, G-protein coupled receptor 6C.l
Supplier: Assay Genie
Supplier-Nr: HDFP300

Properties

Conjugate: No
Host: Human cells
Species reactivity: human

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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