LRRC8B (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2412 Sequence: atgattacac taactgagct aaaatgctta gcagatgctc agtcatctta tcacatctta aaaccatggt gggacgtctt ctggtattac atcacactga tcatgctgct ggtggccgtg ctggccggag ctctccagct gacgcagagc agggttctgt gctgtcttcc atgcaaagtg gaatttgaca atcactgtgc cgtgccttgg gacatcctga aagccagcat gaacacatcc tctaatcctg ggacaccgct tccgctcccc ctccgaattc agaatgacct ccaccgacag cagtactcct atattgatgc cgtctgttac gagaaacagc tccattggtt tgcaaagttt ttcccctatc tggtgctctt gcacacgctc atctttgcag cctgcagcaa cttttggctt cactacccca gtaccagttc caggctcgag cattttgtgg ccatccttca caagtgcttc gattctccat ggaccacccg cgccctttca gaaacagtgg ctgagcagtc agtgaggcct ctgaaactct ccaagtccaa gattttgctt tcgtcctcag ggtgttcagc tgacatagat tccggcaaac agtcattgcc ctacccacag ccaggtttgg agtcagctgg catagaaagc ccaacttcca gtgtcctgga caagaaggag ggtgaacagg ccaaagccat ctttgaaaaa gtgaaaagat tccgcatgca tgtggagcag aaggacatca tttatagagt atatctgaaa cagataatag tcaaagtcat tttgtttgtg ctcatcataa cttatgttcc atatttttta acccacatca ctcttgaaat cgactgttca gttgatgtgc aggcttttac aggatataag cgctaccagt gtgtctattc cttggcagaa atctttaagg tcctggcttc attttatgtc attttggtta tactttatgg tctgacctct tcctacagcc tgtggtggat gctgaggagt tccctgaagc aatattcctt tgaggcgtta agagaaaaaa gcaactacag tgacatccct gatgtcaaga atgactttgc cttcatcctt catctggctg atcagtatga tcctctttat tccaaacgct tctccatatt cctatcagag gtcagtgaga acaaactgaa acagatcaac ctcaataatg aatggacagt tgagaaactg aaaagtaagc ttgtgaaaaa tgcccaggac aagatagaac tgcatctttt tatgctcaac ggtcttccag acaatgtctt tgagttaact gaaatggaag tgctaagcct ggagcttatc ccagaggtga agctgccctc tgcagtctca cagctggtca acctcaagga gcttcgtgtg taccattcat ctctggtcgt agaccatcct gcactggcct ttctagagga gaatttaaaa atcctccgcc tgaaatttac tgaaatggga aaaatcccac gctgggtatt tcacctcaag aatctcaagg aactttatct ttcgggctgt gttctccctg aacagttgag tactatgcag ttggagggct ttcaggactt aaaaaatcta aggaccctgt acttgaagag cagcctctcc cggatcccac aagttgttac agacctcctg ccttcattgc agaaactgtc ccttgataat gagggaagca aactggttgt gttgaacaac ttgaaaaaga tggtcaatct gaaaagccta gaactgatca gctgtgacct ggaacgcatc ccacattcca ttttcagcct gaataatttg catgagttag acctaaggga aaataacctt aaaactgtgg aagagatcat tagctttcag catcttcaga atctttcctg cttaaagttg tggcacaata acattgctta tattcctgca cagattgggg cattatctaa cctagagcag ctctctttgg accataataa tattgagaat ctgcccttgc agcttttcct atgcactaaa ctacattatt tggatctaag ctataaccac ttgaccttca ttccagaaga aatccagtat ctgagtaatt tgcagtactt tgctgtgacc aacaacaata ttgagatgct accagatggg ctgtttcagt gcaaaaagct gcagtgttta cttttgggga aaaatagctt gatgaatttg tcccctcatg tgggtgagct gtcaaacctt actcatctgg agctcattgg taattacctg gaaacacttc ctcctgaact agaaggatgt cagtccctaa aacggaactg tctgattgtt gaggagaact tgctcaatac tcttcctctc cctgtaacag aacgtttaca gacgtgctta gacaaatgtt Protein function: Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24790029, PubMed:26824658, PubMed:28193731). The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition (PubMed:24790029, PubMed:26824658, PubMed:28193731). [The UniProt Consortium]