GSPT2 (Vector pUC, Accession No. BC036077)

Length: 1887 Sequence: atggattcgg gtagcagcag cagcgactcg gcgcccgatt gctgggacca ggtggacatg gaatccacgg ggtcggcccc gagcggggat ggagtctcct ctgcggtggc cgaggcccag cgcgagcccc tcagctcggc tttcagccgt aagctcaacg tcaacgccaa gcccttcgtg cctaacgtac acgccgcgga gttcgtgccg tccttcctgc ggggcccgac tcagccgccc accctcccgg ccggctccgg cagcaacgat gaaacctgca ccggcgcggg ataccctcaa ggtaaaagga tgggacgggg ggcacctgtg gaaccttccc gagaggaacc gttagtgtcg cttgaaggtt ccaattcagc cgttaccatg gaactttcag aacctgttgt agaaaatgga gaggtggaaa tggccctaga agaatcatgg gagcacagta aagaagtaag tgaagccgag cctgggggtg gttcctcggg agattcaggg cccccagaag aaagtggcca ggaaatgatg gaggaaaaag aggaaataag aaaatccaaa tctgtgatcg taccctcagg tgcacctaag aaagaacacg taaatgtagt attcattggc catgtagacg ctggcaagtc aaccatcgga ggacagataa tgtttttgac tggaatggtt gacaaaagaa cactggagaa atatgaaaga gaagctaagg aaaaaaacag agaaacctgg tatttgtcct gggccttaga tacaaatcag gaggaacgag acaagggtaa aacagtcgaa gtgggtcgtg cctattttga aacagaaagg aaacatttca caattttaga tgcccctggc cacaagagtt ttgtcccaaa tatgattggt ggtgcttctc aagctgattt ggctgtgctg gtcatctctg ccaggaaagg agagtttgaa actggatttg aaaaaggtgg acagacaaga gaacatgcga tgttggcaaa aacggcaggg gtaaaacatt taatagtgct tattaataag atggatgatc acacagtaaa ttggagcatc gagagatatg aagaatgtaa agaaaaactg gtgccctttt tgaaaaaagt aggcttcagt ccaaaaaagg acattcactt tatgccctgc tcaggactga ccggagcaaa tattaaagag cagtcagatt tctgcccttg gtacactgga ttaccattta ttccgtattt ggataacttg ccaaacttca acagatcaat tgatggacca ataagactgc caattgtgga taagtacaaa gatatgggca ctgtggtcct gggaaagctg gaatccgggt ccatttttaa aggccagcag ctcgtgatga tgccaaacaa gcacaatgta gaagttcttg gaatactttc tgatgatact gaaactgatt ttgtagcccc aggtgaaaac ctcaaaatca gactgaaggg aattgaagaa gaagagattc ttccaggatt catactttgt gatcctagta acctctgcca ttctggacgc acgtttgatg ttcagatagt gattattgag cacaaatcca tcatctgccc aggttataat gcggtgctgc acattcatac ttgtattgag gaagttgaga taacagcgtt aatctccttg gtagacaaaa aatcaggaga aaaaagtaag acacgacccc gcttcgtgaa acaagatcaa gtatgcattg ctcgtttaag gacagcagga accatctgcc tcgagacgtt caaagatttt cctcagatgg gtcgttttac tttaagagat gagggtaaga ccattgcaat tggaaaagtt ctgaaattgg tccaagagaa Protein function: Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. [The UniProt Consortium]