FAM134B (Vector pENTR223.1, Accession No. BC073132)

Length: 1071 Sequence: atgcctgaag gtgaagactt tggaccaggc aaaagctggg aagttatcaa ttccaaacca gatgaaagac ccaggctcag ccactgtatt gcagaatcat ggatgaattt cagcatattt cttcaagaaa tgtctctttt taaacagcag agccctggca agttttgtct cctggtctgt agtgtgtgca cattttttac gatcttggga agttacattc ctggggttat actcagctat ctactgttac tgtgtgcatt tttgtgtcca ttgtttaaat gtaatgatat tggacaaaaa atttacagca aaattaagtc agttctgctg aaactggatt ttggaattgg agaatatatt aatcagaaga aacgtgagag atctgaagca gataaagaaa aaagtcacaa agatgacagt gaattagact tttcagctct ttgtcctaag attagcctca cggttgctgc caaagagtta tctgtgtctg acacagacgt ctcagaggta tcctggactg ataatgggac cttcaacctt tcagaaggat acactccaca gacagacact tctgatgatc ttgaccgacc cagtgaggaa gttttctcta gagatctttc agattttcca tctctagaaa atggcatggg aacaaatgat gaagatgaat taagccttgg tttgcccact gagctcaaga gaaagaagga acagttggac agtggtcaca gaccaagcaa agagacgcaa tcagcagctg gtctcaccct tcctctgaac agtgaccaaa cctttcacct gatgagcaac ctggctgggg atgttatcac agctgcagtg actgcagcta tcaaagacca gttagagggt gtgcagcaag cactttctca ggctgccccc atcccagaag aggacacaga cactgaagaa ggtgatgact ttgaactact tgaccagtca gagctggatc aaattgagag tgaattggga cttacacaag accaggaagc agaagcacag caaaataaga agtcttcagg tttcctttca aatctgctgg gaggccatta Protein function: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720). [The UniProt Consortium]