BEND3 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2487 Sequence: ATGAACTCAA CTGAATTCAC CGAAGATGTA GAAGAAGTTC TAAAAAGTAT CACTGTGAAA GTGGAGACAG AGGCTGAAGA TGCTGCTCTG GACTGCTCCG TGAATTCCAG GACTTCTGAG AAGCACTCTG TGGACAGCGT CCTCACTGCC CTGCAGGACT CCAGCAAACG AAAGCAGCTG GTCAGCGATG GCCTGCTAGA CTCTGTCCCC GGCGTGAAGA GGAGGCGGCT GATCCCCGAG GCTCTCCTAG CAGGCATGCG GAACCGTGAG AACAGCTCGC CCTGCCAAGG CAATGGTGAG CAGGCCGGCA GGGGCAGGAG CCTGGGCAAT GTGTGGCCTG GAGAGGAGGA GCCCTGCAAC GATGCCACCA CCCCTTCCTA CAAGAAGCCT CTGTATGGCA TCTCGCACAA GATCATGGAG AAGAAGAATC CTCCCTCGGG GGACCTGCTA AACGTGTACG AGCTCTTTGA GAAGGCAAAC GCCAGCAACA GCCCCTCGTC ACTGCGGCTC CTGAATGAGC CACAGAAGCG GGACTGTGGC AGCACCGGGG CAGGCACTGA CAACGACCCC AACATCTACT TCCTGATCCA GAAGATGTTC TACATGCTGA ACACCCTCAC GTCCAACATG TCCCAGCTGC ACAGCAAGGT GGACCTGCTC TCCCTTGAGG TGAGCCGCAT CAAGAAGCAG GTGAGCCCCA CTGAGATGGT GGCCAAATTC CAGCCGCCCC CTGAGTACCA GCTCACAGCC GCAGAGCTCA AGCAGATCGT GGACCAGAGC CTGTCAGGGG GGGACCTGGC CTGCCGCTTG CTGGTGCAGC TCTTCCCCGA GCTCTTCAGC GACGTGGACT TCTCCCGGGG CTGCAGTGCC TGTGGCTTTG CGGCCAAGCG CAAGCTGGAG TCGCTGCACC TGCAGCTCAT CCGCAACTAT GTGGAGGTCT ACTACCCCTC GGTGAAGGAC ACGGCTGTGT GGCAGGCCGA GTGCCTGCCC CAGCTGAACG ACTTCTTCAG CCGCTTCTGG GCCCAGCGGG AAATGGAGGA CAGCCAGCCC AGCGGCCAGG TCGCCAGCTT CTTTGAGGCA GAGCAGGTGG ACCCCGGCCA CTTCCTGGAC AACAAAGACC AGGAGGAGGC CCTGTCTCTT GACCGGAGCA GCACCATCGC CTCAGACCAC GTGGTGGACA CGCAGGACCT CACTGAGTTC CTGGACGAAG CCTCCTCACC AGGCGAGTTT GCCGTCTTCC TCCTCCACCG GCTCTTCCCC GAGCTCTTCG ACCACCGCAA GCTGGGTGAA CAGTACAGCT GCTACGGGGA CGGTGGAAAG CAGGAGCTGG ACCCGCAGCG GCTGCAGATC ATCCGCAACT ACACGGAGAT CTACTTCCCT GACATGCAGG AGGAGGAGGC CTGGCTGCAG CAGTGTGCCC AGCGCATCAA CGACGAGCTC GAGGGCCTGG GGCTGGACGC GGGCAGTGAA GGCGACCCCC CGCGTGATGA CTGCTACGAC TCCTCCAGTC TGCCCGACGA CATCTCAGTG GTCAAGGTGG AGGACAGCTT CGAGGGCGAG CGGCCGGGTC GCCGCTCCAA GAAGATCTGG CTGGTGCCCA TCGACTTCGA CAAGTTAGAG ATCCCCCAGC CTGACTTCGA GGTGCCCGGT GCCGACTGCC TGCTCAGCAA GGAGCAGCTA CGCAGCATCT ACGAGAGCAG CCTGTCCATC GGCAACTTCG CCTCGCGCCT GCTGGTGCAC CTGTTCCCCG AGCTCTTCAC GCACGAGAAC CTGCGCAAGC AGTACAGCTG CAGCGGCTCC CTGGGCAAGA AGCAGCTGGA CCCCTCCCGC ATCAAGCTCA TCCGCCACTA CGTGCAGCTG CTCTACCCAC GCGCCAAAAA CGACCGCGTC TGGACCCTGG AGTTCGTGGG CAAACTGGAT GAGCGCTGCC GGCGCCGGGA CACGGAGCAA AGGCGCTCCT ACCAGCAGCA GCGCAAGGTC CACGTGCCGG GCCCTGAGTG CAGAGACTTG ACCAGCTATG CAATCAACCC CGAGAGGTTC CGGGAGGAGT TTGAGGGGCC CCCACTGCCC CCCGAGAGGA GCAGCAAGGA CTTTTGCAAG ATCCCCTTGG ACGAGCTGGT GGTCCCCTCG CCTGACTTCC CGGTGCCTTC TCCCTACCTG CTGTCTGACA AGGAGGTGCG TGAGATCGTG CAGCAGAGCC TCTCCGTGGG CAACTTTGCC GCCCGGCTCC TCGTCCGCCT GTTTCCCGAA CTCTTCACCG CCGAGAACCT CCGGCTGCAG TACAACCATT CCGGGGCTTG CAACAAGAAG CAACTGGACC CCACGCGGCT GCGGCTCATC CGCCACTACG TGGAAGCCGT CTACCCGGTG GAGAAGATGG AGGAGGTGTG GCACTACGAA TGTATCCCCA GCATCGATGA GAGGTGCCGC CGCCCCAACA GGAAAAAATG CGACATCCTC AAGAAAGCAA AGAAAGTGGA Protein function: Transcriptional repressor which associates with the NoRC (nucleolar remodeling complex) complex and plays a key role in repressing rDNA transcription. The sumoylated form modulates the stability of the NoRC complex component BAZ2A/TIP5 by controlling its USP21-mediated deubiquitination (PubMed:21914818, PubMed:26100909). Binds to unmethylated major satellite DNA and is involved in the recruitment of the Polycomb repressive complex 2 (PRC2) to major satellites. Stimulates the ERCC6L translocase and ATPase activities (PubMed:28977671). [The UniProt Consortium]