ATAD2 (Vector pENTR223.1, Accession No. BC019909)

Length: 1089 Sequence: atggaccttt catctgtaat cagtaaaatt gatctacaca agtatctgac tgtgaaagac tatttgagag atattgatct aatctgtagt aatgccttag aatacaatcc agatagagat cctggagatc gtcttattag gcatagagcc tgtgctttaa gagatactgc ctatgccata attaaagaag aacttgatga agactttgag cagctctgtg aagaaattca ggaatctaga aagaaaagag gttgtagctc ctccaaatat gccccgtctt actaccatgt gatgccaaag caaaattcca ctcttgttgg tgataaaaga tcagacccag agcagaatga aaagctaaag acaccgagta ctcctgtggc ttgcagcact cctgctcagt tgaagaggaa aattcgcaaa aagtcaaact ggtacttagg caccataaaa aagcgaagga agatttcaca ggcaaaggat gatagccaga atgccataga tcacaaaatt gagagtgata cagaggaaac tcaagacaca agtgtagatc ataatgagac cggaaacaca ggagagtctt cggtggaaga aaatgaaaaa cagcaaaatg cctctgaaag caaactggaa ttgagaaata attcaaatac ttgtaatata gagaatgagc ttgaagactc taggaagact acagcatgta cagaattgag agacaagatt gcttgtaatg gagatgcttc tagctctcag ataatacata tttctgatga aaatgaagga aaagaaatgt gtgttctgcg aatgactcga gctagacgtt cccaggtaga acagcagcag ctcatcactg ttgaaaaggc tttggcaatt ctttctcagc ctacaccctc acttgttgtg gatcatgagc gattaaaaaa tcttttgaag actgttgtta aaaaaagtca aaactacaac atatttcagt tggaaaattt gtatgcagta atcagccaat gtatttatcg gcatcgcaag gaccatgata aaacatcact tattcagaaa atggagcaag aggtagaaaa cttcagttgt Protein function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. [The UniProt Consortium]