28 products were found matching "K22531"!

BAY-850 is an inhibitor of the ATPase family AAA domain-containing protein 2 (ATAD2, IC50 = 22 nM in a time-resolved FRET assay using a tetra-acetylated histone H4 peptide). It is selective for ATAD2 over a panel of 32 bromodomain family proteins, including ATAD2B, a panel of 354 kinases, and a panel of 25 G...

Human Bromodomain ATAD2A, amino acids 981 ? 1108 (GenBank Accession No. NM_014109) with N-terminal HIS-tag, MW = 16.2 kDa, expressed in an E. coli expression system.

Human bromodomain ATPase family, AAA domain containing 2B (variant 1), amino-acids 951 - 1080, (GenBank Accession No. NM_017552) with N-terminal HIS-tag, MW = 15.9 kDa, expressed in an E. coli expression system.

Human Bromodomain ATAD2A, amino-acids 981 ? 1108 (GenBank Accession No. NM_014109) with N-terminal GST-tag, MW = 42 kDa, expressed in an E. coli expression system.

Human bromodomain ATPase family, AAA domain containing 2B (variant 1), amino-acids 953 - 1080, (GenBank Accession No. NM_017552) with N-terminal GST-tag, MW = 42 kDa, expressed in an E. coli expression system.

The ATAD2A Inhibitor Screening Assay Kit is designed to measure the inhibition of ATAD2A bromodomain binding to its substrate. The kit comes in a convenient AlphaLISA(R) format, with biotinylated histone peptide substrate, assay buffer, detection buffer and purified ATAD2A for 384 assays.

The ATAD2B Inhibitor Screening Assay Kit is designed to measure the inhibition of ATAD2B binding to its substrate. The kit comes in a convenient AlphaLISA format, with enough biotinylated histone peptide substrate, assay buffer, detection buffer and purified GST-tagged ATAD2B bromodomain to perform a total of 384...

The ATAD2A TR-FRET Assay Kit is designed to measure the inhibition of ATAD2A binding to its substrate in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications.

The ATAD2B TR-FRET Assay Kit is designed to measure the inhibition of ATAD2B binding to its substrate in a homogeneous 384 reaction format. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications. The assay procedure is straightforward...

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in linking protein complexes to acetylated nucleosomes, thereby controlling chromatin...

Protein function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone...

Protein function: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone...