Azidoindolene 1

UR-144 (Cay-11502) and XLR11 (Cay-11565) are potent synthetic cannabinoids (CBs) that have been identified as adulterants of herbal products. Azidoindolene 1 is structurally similar to UR-144, XLR11, and a number of additional synthetic CBs with a hydrazide linking the tetramethylcyclopropyl group to the aminoalkylindole group. The physiological and toxicological properties of this compound are not known. Typically, a tetramethylcyclopropyl group confers selectivity for the peripheral CB2 receptor, and the addition of substituents at the N1-amine of the aminoalkylindole group is necessary for high affinity at either CB1 or CB2. This product is intended for forensic and research applications.Formal Name: 2,2,3,3-tetramethyl-cyclopropanecarboxylic acid (2Z)-2-[1-(5-fluoropentyl)-1,2-dihydro-2-oxo-3H-indol-3-ylidene]hydrazide. CAS Number: 1364933-69-6. Molecular Formula: C21H28FN3O2. Formula Weight: 373.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml. lambdamax: 225, 250, 272, 324 nm. SMILES: O=C1/C(C2=CC=CC=C2N1CCCCCF)=N\NC(C3C(C)(C)C3(C)C)=O. InChi Code: InChI=1S/C21H28FN3O2/c1-20(2)17(21(20,3)4)18(26)24-23-16-14-10-6-7-11-15(14)25(19(16)27)13-9-5-8-12-22/h6-7,10-11,17H,5,8-9,12-13H2,1-4H3,(H,24,26)/b23-16-. InChi Key: PRXCXNXDBMJFFC-KQWNVCNZSA-N.