XY-4

XY-4 is a derivative of 1-palmitoyl-2-hydroxy-sn-glycero-3-PA (1-palmitoyl LPA, Cay-10010094) and an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It induces reporter gene expression in RAW 264.7 macrophages expressing a peroxisome proliferator-response element (PPRE) when used at a concentration of 5 µM. XY-4 does not act as an agonist at lysophosphatidic acid receptor 1 (LPA1), LPA2, or LPA3. It induces platelet aggregation in vitro when used at a concentration of 1 µM. XY-4 induces carotid artery neointima formation in rats.Formal Name: hexadecanoic acid, (1R)-2,2-difluoro-1-[(phosphonooxy)methyl]ethyl ester. CAS Number: 474329-47-0. Molecular Formula: C19H37F2O6P. Formula Weight: 430.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Soluble. SMILES: FC([C@H](OC(CCCCCCCCCCCCCCC)=O)COP(O)(O)=O)F. InChi Code: InChI=1S/C19H37F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(22)27-17(19(20)21)16-26-28(23,24)25/h17,19H,2-16H2,1H3,(H2,23,24,25)/t17-/m1/s1. InChi Key: FNESAIQQDLSXRX-QGZVFWFLSA-N.