Pinane Thromboxane A2

Pinane Thromboxane A2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay19020-500 500 µg -

6 - 10 business days*

74.00€
Cay19020-1 1 mg -

6 - 10 business days*

140.00€
Cay19020-5 5 mg -

6 - 10 business days*

590.00€
Cay19020-10 10 mg -

6 - 10 business days*

1,033.00€
 
Pinane thromboxane A2 (PTA2) is a stable analog of TXA2. It is a TP receptor antagonist and an... more
Product information "Pinane Thromboxane A2"
Pinane thromboxane A2 (PTA2) is a stable analog of TXA2. It is a TP receptor antagonist and an inhibitor of thromboxane synthase. PTA2 inhibits U-46619-induced cat coronary artery constriction (ID50 = 0.1 µM), U-46619-induced aggregation of human platelets (IC50 = 2 µM), and rabbit platelet thromboxane synthase (ID50 = 50 µM). PTA2 does not affect PGI synthase up to a concentration of 100 µM. Formal Name: (5Z)-7-[(1S,2R,3R,5S)-3-[(1E,3S)-3-hydroxy-1-octen-1-yl]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5-heptenoic acid. CAS Number: 71111-01-8. Synonyms: 15(S)-Pinane Thromboxane A2, Pinane TXA2, PTA2. Molecular Formula: C24H40O3. Formula Weight: 376.6. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: >50 mg/ml, DMSO: >25 mg/ml, Ethanol: >100 mg/ml, PBS pH 7.2: >100 µg/ml. SMILES: CCCCC[C@H](O)/C=C/[C@H]1C[C@H]2C[C@H](C2(C)C)[C@@H]1C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C24H40O3/c1-4-5-8-11-20(25)15-14-18-16-19-17-22(24(19,2)3)21(18)12-9-6-7-10-13-23(26)27/h6,9,14-15,18-22,25H,4-5,7-8,10-13,16-17H2,1-3H3,(H,26,27)/b9-6-,15-14+/t18-,19-,20-,21+,22-/m0/s1. InChi Key: OHJIHGVLRDHSDV-BNAVIEMTSA-N.
Keywords: 15(S)-Pinane Thromboxane A2, Pinane TXA2, PTA2, 9alpha,11alpha-(dimethyl)methylene-15S-hydroxy-11a-deoxy-11a-methylene-thromba-5Z,13E-dien-1-oic
Supplier: Cayman Chemical
Supplier-Nr: 19020

Properties

Application: Thromboxane synthase inhibitor
MW: 376.6 D
Formula: C24H40O3
Purity: >98%
Format: Solution

Database Information

CAS : 71111-01-8| Find alternatives
KEGG ID : K01832 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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