omega-3 Arachidonic Acid-d8

omega-3 Arachidonic acid-d8 contains eight deuterium atoms at the 8, 9, 11, 12, 14, 15, 17, and 18 positions. It is intended for use as an internal standard for the quantification of omega-3 arachidonic acid by GC- or LC-mass spectrometry. omega-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. omega-3 fatty acids are now known to be essential for infant growth and development and to protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki value of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.Formal Name: 8Z,11Z,14Z,17Z-eicosatetraenoic-8,9,11,12,14,15,17,18-d8 acid. Synonyms: omega-3 AA-d8, FA 20:4-d8. Molecular Formula: C20H24D8O2. Formula Weight: 312.5. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: 0.1 M Na2CO3: 1.7 mg/ml, DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: Miscible. SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\CCCCCCC(=O)O. InChi Code: InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13H,2,5,8,11,14-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-/i3D,4D,6D,7D,9D,10D,12D,13D. InChi Key: HQPCSDADVLFHHO-LDWVABASSA-N. Side Chain Carbon Sum: 20:4.