165 products were found matching "K01897"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. ACSL5 antibody detects Long chain fatty acid CoA ligase 5, an enzyme that activates long chain fatty acids for lipid metabolism, beta oxidation, and membrane synthesis. Encoded by the ACSL5 gene on chromosome 10q25.2, this enzyme belongs to...

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role...

Triacsin C, originally isolated from Streptomyces sp., is an inhibitor of long fatty acid acyl-CoA synthetase (IC50 = 6.3 µM in Raji cells). It has been shown to interfere with lipid metabolism by inhibiting the de novo synthesis of triglycerides, diglycerides, and cholesterol esters. It is also known to act as a...

Long-chain acyl-CoA synthetase 4 (ACSL4) is a CoA ligase and member of the ACSL family. It is composed of an N-terminal membrane-binding domain, a transmembrane domain, an adenosine adaptor region, and a C-terminal catalytic domain. ACSL4 is primarily found in the mitochondria, peroxisomes, endoplasmic reticulum...

Protein function: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:21242590, PubMed:22633490, PubMed:24269233). Preferentially activates arachidonate and eicosapentaenoate as substrates...

Protein function: Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses arachidonate and eicosapentaenoate as substrates. [The UniProt Consortium]

Protein function: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially uses palmitoleate, oleate and linoleate (PubMed:24269233). Preferentially...

LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4, IC50 = 0.38 µM). It is selective for ACSL4 over ACSL3 (IC50 = >50 µM) and peroxisome proliferator-activated receptor gamma (PPARgamma, IC50 = >10 µM).Formal Name: methyl (E)-3-(4-(2-(N-methylbenzamido)ethoxy)phenyl)acrylate. Molecular Formula:...

Protein function: Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses arachidonate and eicosapentaenoate as substrates. [The UniProt Consortium]

Protein function: Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses arachidonate and eicosapentaenoate as substrates. [The UniProt Consortium]

Protein function: Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage. Utilizes a wide range of saturated...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Acyl-CoA synthetase long-chain family member 4, FACL4, Fatty-acid-Coenzyme A ligase, long-chain 4 Protein function: Activation of long-chain fatty acids for both synthesis of cellular lipids,...